DPP-4 inhibitory activity and myocardial salvaging effects of Commiphora mukul in experimental diabetes

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منابع مشابه

Cultivation and Conservation of Guggulu (Commiphora mukul)

Guggulu (Commiphora mukul) is about 2-3.5 mt heighted plant of Burceraceae family. The plant grows wild in the arid, rocky tracts, also in low rainy and hot areas. The part used in medicinal preparation is resin, collected by tapping the barks. Guggulu deserves high values in Ayurvedic medicines. Guggulu is Rasayana, Vatakaphaghna, and used in various diseases. Due to high values and excessive ...

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Effect of Commiphora mukul extract on cardiac dysfunction and ventricular function in isoproterenol-induced myocardial infarction.

In present study, hydroalcoholic extract of C. mukul significantly improved the cardiac function and prevented myocardial ischemic impairment manifested in the form of increased heart rate, decreased arterial pressure, increased left ventricular end diastolic pressure, and altered myocardial contractility indices. C. mukul treatment additionally also produced a significant increase in lactate d...

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Hypocholesterolemic effect of Commiphora mukul resin (guggal).

Alcohollc extract of C. mulnd resin (guggal) and one pure steroid isolated from this extract, when administered orally at a dose of 25-50 mgjkg body weight, reduced the serum cholesterol level in normal and triton-induced byperUpemlc rats and cholesterol-fed byperlipemIc rabbits. Both guggal extract and the steroid showed only slight inhibition of cholesterol biosynthesIs 85 compared to p_chlor...

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The anti-diabetic and antioxidant effects of a combination of Commiphora mukul, Commiphora myrrha and Terminalia chebula in diabetic rats

Objective: Effects of Commiphora mukul and Commiphora myrrha ethanolic extracts and Terminalia chebula<span style...

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In Vitro Studies on Thyrogenic Effect of Commiphora Mukul (guggulu)

The results of this study has revealed a significant increase in I(131) uptake of cultivated thyroid gland in the media containing petroleum ether extract of Commiphora mukul. Besides, T(3) resin uptake, protein bound iodine as well as free thyroxine index in the media are also observed to be significantly (P 0.001) increased. When explants are cultivated in the media containing melatonin, ther...

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ژورنال

عنوان ژورنال: International Journal of Basic & Clinical Pharmacology

سال: 2019

ISSN: 2279-0780,2319-2003

DOI: 10.18203/2319-2003.ijbcp20190668